The spectroscopic monitoring of chemical reactions in the mid-IR is an established method to determine optimal reaction conditions, to identify the end-point of a reaction or to gather information about the reaction order and path. The measurement in a flow-through setup, that passes the reaction medium constantly over an ATR-crystal in a closed cycle, constitutes an efficient method. During the whole reaction, spectra are recorded software controlled at regular intervals. The Bruker ALPHA FT-IR spectrometer in combination with the temperature controlled diamond ATR-unit und a specially designed flow-through cell is a cost effective, robust and compact combination for the monitoring of reactions with a temporal resolution of up to five seconds.
Bruker offers MATRIX-F FT-NIR spectrometers as the complete solution for your Process Control & Monitoring needs. In addition, the MID-IR MATRIX-MF spectrometer is also available. Both spectrometers with a wide variety of sampling configurations, ideal reaction monitoring platform for research, pilot plants, and production environments.
Real-time monitoring of small-scale chemical batch reactions with Bruker's MATRIX spectrometer provides huge benefits to the future manufacturing process. Not having to wait for a lab analysis and a tighter control of the reaction detects critical problems much earlier and helps to select the right criteria for a safe and scalable route.